During pregnancy, when is Tdap recommended?

• A. Between 27 and 36 weeks gestation
• B. After delivery
• C. Only if there is exposure
• D. Not recommended

Answer: (A)

Getting Tdap during pregnancy is about protecting the newborn when they’re most vulnerable. The best time is between 27 and 36 weeks gestation because antibodies rise in the mother and placental transfer to the baby increases during this window. Vaccinating in this period optimizes the amount of protective antibodies the newborn receives at birth, helping guard against pertussis in the first months of life. If vaccination occurs after delivery, the baby won’t benefit from maternal antibodies in those early weeks, and delaying vaccination until exposure isn’t preventive. For these reasons, administering Tdap during the 27–36 week window is the preferred approach, and it’s recommended during each pregnancy regardless of prior Tdap status.