What is the preferred cervical cancer screening method according to ACS and 2024 USPSTF?

• A. Visual inspection with acetic acid annually
• B. Pap smear every year
• C. Co-testing every 3 years
• D. Primary HPV testing every five years

Answer: (D)

The main idea being tested is which screening approach cervical cancer guidelines now favor for average‑risk women. HPV testing is more sensitive than cytology alone at catching precancerous changes, so using an HPV test as the primary screen allows a longer interval between tests while maintaining safety.

According to ACS and the 2024 USPSTF guidance, the preferred method is primary HPV testing every five years for average‑risk women. This means starting screening at the recommended age and using an HPV test alone, with a 5‑year interval if the result is negative. Alternatives exist and are acceptable: cytology (Pap) alone every 3 years, or cotesting (Pap plus HPV) every 5 years. Visual inspection with acetic acid is not used as a standard screening method in the U.S. for average‑risk individuals.

So the best answer is the HPV test used as the primary screen every five years.