Which breast skin finding is associated with potential malignancy?

• A. Erythema nodosum
• B. Varicosities
• C. Dry skin
• D. Peau d'orange

Answer: (D)

The main concept here is recognizing breast skin changes that raise concern for cancer. Peau d'orange, the orange-peel texture of the skin, occurs when a tumor obstructs lymphatic drainage, causing regional edema and skin tethering. This pattern is highly suspicious for breast malignancy, especially inflammatory breast cancer, and it often signals a need for urgent imaging and tissue diagnosis. The skin may appear thickened, pitted, warm, and may show dimpling without a distinct lump.

Erythema nodosum would present as tender red nodules typically on the shins and is not a breast cancer sign. Varicosities are dilated veins and dry skin is nonspecific; neither pattern points toward breast malignancy. If peau d'orange is observed, proceed with appropriate breast imaging (mammography and ultrasound, with MRI if indicated) and biopsy as guided by imaging and clinical findings.